You may be fine with ISO-style arrangement as it's common in the US or EMD agent status within EEA/UK if your business model is simple, you put fate your business, its risk appetites, and customer due diligence. In most cases, your expenses can be limited to white-label setup fees imposed by︀ issuer, monthly minimum commitments and baseline costs.
Otherwise (and especially if your plan involves offering︁ crypto top ups) there's a good chance you would need to have at least one︂ state-level money transmitting license and FINCEN registration with all respective caveats.
Many similar businesses (namely,︃ those ones who cater to needs of global media buyers dealing with crypto top ups)︄ elect to set up MSB registered in Canada.