If i were American, and︀ wasn't intending to live in the US or knew in the future the probabilities of︁ wealth generation.
I'd probably ensure my kids first had their US Citizenship, then consider paying︂ exit taxes and moving abroad whilst the unrealised probable investment(s) did their things.
For example,︃ a investment that pays 1.5-2.5m would provide a comfortable life outside of the US, whereas︄ in the US it wouldn't due to the trappings of society.
Whilst the kids would︅ be able to make their own choice.
Otherwise you may as well continue to pay︆ uncle sam.